HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Aminopiperidine-2,6-dione hydrochloride → Pomalidomide Impurity 10
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Aminopiperidine-2,6-dione hydrochloride | HCID 134548 | — |
| Reactant | HCID 67861099 | HCID 67861099 | — |
| Product | Pomalidomide Impurity 10 | HCID 72736581 | — |
Reaction Steps
reacting 3-amino-4-hydroxyphthalic acid with 3-aminopiperidine-2,6-dione hydrochloride, or an enantiomer or a mixture of enantiomers thereof; to form 4-amino-2-(2,6-dioxopiperidin-3-yl)-5-hydroxyisoindoline-1,3-dione.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09133161B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-3ed89e9f1e0f44e6abe206855b556c03 |
| Source note | uspto-grants-2015_09 |