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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2277163Generated: November 2, 2026

N-((2S)-1-(1,3-benzoxazol-6-yloxy)propan-2-yl)acetamide → N-((2S)-1-((2-(5-chloro-6-(cyclopropylmethoxy)pyridin-3-yl)-1,3-benzoxazol-6-yl)oxy)propan-2-yl)acetamide

https://huagongshe.com/reaction/2277163

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-((2S)-1-(1,3-benzoxazol-6-yloxy)propan-2-yl)acetamideHCID 86731211—
Reactant5-Bromo-3-chloro-2-(cyclopropylmethoxy)pyridineHCID 86731215—
ProductN-((2S)-1-((2-(5-chloro-6-(cyclopropylmethoxy)pyridin-3-yl)-1,3-benzoxazol-6-yl)oxy)propan-2-yl)acetamideHCID 86731216—

Reaction Steps

Using N-((2S)-1-(1,3-benzoxazol-6-yloxy)propan-2-yl)acetamide and 5-bromo-3-chloro-2-(cyclopropylmethoxy)pyridine, and in the same manner as in Step B of Example 22, the title compound was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09133129B2
Source datasetuspto-grants-2015_09
ORD IDord-21cbf7d0838b44458825df8cbd28711f
Source noteuspto-grants-2015_09