Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2277191Generated: October 30, 2026

HCID 86731249, compound → HCID 136341405, compound

https://huagongshe.com/reaction/2277191

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 86731249HCID 86731249—
CatalystHCID 178418390HCID 178418390—
SolventTetrahydrofuranHCID 8028—
ProductHCID 136341405HCID 13634140596.3%

Reaction Steps

A mixture of N-((2S)-1-((2-(4-(benzyloxy)-3-fluorophenyl)-7-fluoro-1,3-benzoxazol-6-yl)oxy)propan-2-yl)acetamide (1.05 g), 10% palladium-carbon (containing water (50%), 1.00 g) and THF (10 mL) was stirred at room temperature for 30 min under a hydrogen atmosphere. The catalyst was removed by filtration, and the obtained filtrate was concentrated under reduced pressure to give the title compound (810 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09133129B2
Source datasetuspto-grants-2015_09
ORD IDord-e6537c2a4e4e492b970bee55158c4736
Source noteuspto-grants-2015_09