Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2277254Generated: October 31, 2026

5-Bromo-2-(cyclopropylmethoxy)pyrimidine → N-((2S)-1-((2-(2-(cyclopropylmethoxy)pyrimidin-5-yl)-1,3-benzoxazol-6-yl)oxy)propan-2-yl)acetamide

https://huagongshe.com/reaction/2277254

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Bromo-2-(cyclopropylmethoxy)pyrimidineHCID 63868413—
ReactantN-((2S)-1-(1,3-benzoxazol-6-yloxy)propan-2-yl)acetamideHCID 86731211—
ProductN-((2S)-1-((2-(2-(cyclopropylmethoxy)pyrimidin-5-yl)-1,3-benzoxazol-6-yl)oxy)propan-2-yl)acetamideHCID 86731326—

Reaction Steps

Using 5-bromo-2-(cyclopropylmethoxy)pyrimidine and N-((2S)-1-(1,3-benzoxazol-6-yloxy)propan-2-yl)acetamide, and in the same manner as in Step B of Example 22, the title compound was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09133129B2
Source datasetuspto-grants-2015_09
ORD IDord-c2de321a6e5f4dfca896131783bbf4e8
Source noteuspto-grants-2015_09