HuagongsheHuagongshe Chemistry Print Report · For research reference only
(1-Fluorocyclopropyl)methanol → N-((2S)-1-((2-(3,5-difluoro-4-((1-fluorocyclopropyl)methoxy)phenyl)-1,3-benzoxazol-6-yl)oxy)propan-2-yl)acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (1-Fluorocyclopropyl)methanol | HCID 67149022 | — |
| Reactant | N-((2S)-1-((2-(4-(benzyloxy)-3,5-difluorophenyl)-1,3-benzoxazol-6-yl)oxy)propan-2-yl)acetamide | HCID 86731330 | — |
| Product | N-((2S)-1-((2-(3,5-difluoro-4-((1-fluorocyclopropyl)methoxy)phenyl)-1,3-benzoxazol-6-yl)oxy)propan-2-yl)acetamide | HCID 86731329 | — |
Reaction Steps
Using N-((2S)-1-((2-(4-(benzyloxy)-3,5-difluorophenyl)-1,3-benzoxazol-6-yl)oxy)propan-2-yl)acetamide and (1-fluorocyclopropyl)methanol, and in the same manner as in Step A and Step B of Example 4, the title compound was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09133129B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-8dbf14d6980a44fdb309168582917ddf |
| Source note | uspto-grants-2015_09 |