Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2277283Generated: November 1, 2026

4-(Cyclopropylmethoxy)-2-methylbenzoic acid → N-((2S)-1-((2-(4-(cyclopropylmethoxy)-2-methylphenyl)[1,3]oxazolo[4,5-c]pyridin-6-yl)oxy)propan-2-yl)acetamide

https://huagongshe.com/reaction/2277283

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Cyclopropylmethoxy)-2-methylbenzoic acidHCID 58047350—
ReactantN-((2S)-1-((4-chloro-5-nitropyridin-2-yl)oxy)propan-2-yl)acetamideHCID 86731225—
ProductN-((2S)-1-((2-(4-(cyclopropylmethoxy)-2-methylphenyl)[1,3]oxazolo[4,5-c]pyridin-6-yl)oxy)propan-2-yl)acetamideHCID 86731366—

Reaction Steps

Using 4-(cyclopropylmethoxy)-2-methylbenzoic acid and N-((2S)-1-((4-chloro-5-nitropyridin-2-yl)oxy)propan-2-yl)acetamide, and in the same manner as in Step B and Step C of Example 31, the title compound was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09133129B2
Source datasetuspto-grants-2015_09
ORD IDord-13b0a1232aff4e38bd47b6164678071b
Source noteuspto-grants-2015_09