HRID2277293

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID69020088

4-[(2,2-Difluorocyclopropyl)methoxy]benzoic acid

C11H10F2O3

结构：C[C@@H](COc1ncc([N+](=O)[O-])c(OCc2ccccc2)n1)NC(=O)OC(C)(C)C

HCID86731375

Carbamic acid, N-[(1S)-1-methyl-2-[[5-nitro-4-(phenylmethoxy)-2-pyrimidinyl]oxy]ethyl]-, 1,1-dimethylethyl ester

C19H24N4O6

PRODUCTS

生成物

结构：C[C@@H](COc1ncc(NC(=O)c2ccc(OCC3CC3(F)F)cc2)c(O)n1)NC(=O)OC(C)(C)C

HCID178461782

未命名化合物

PROCEDURE

实验过程

Using tert-butyl ((2S)-1-((4-(benzyloxy)-5-nitropyrimidin-2-yl)oxy)propan-2-yl)carbamate and 4-((2,2-difluorocyclopropyl)methoxy)benzoic acid, and in the same manner as in Step A of Example 4 and Step D of Example 83, the title compound was obtained.