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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2277293Generated: October 29, 2026

4-((2,2-Difluorocyclopropyl)methoxy)benzoic acid → HCID 178461782, compound

https://huagongshe.com/reaction/2277293

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-((2,2-Difluorocyclopropyl)methoxy)benzoic acidHCID 69020088—
Reactanttert-butyl ((2S)-1-((4-(benzyloxy)-5-nitropyrimidin-2-yl)oxy)propan-2-yl)carbamateHCID 86731375—
ProductHCID 178461782HCID 178461782—

Reaction Steps

Using tert-butyl ((2S)-1-((4-(benzyloxy)-5-nitropyrimidin-2-yl)oxy)propan-2-yl)carbamate and 4-((2,2-difluorocyclopropyl)methoxy)benzoic acid, and in the same manner as in Step A of Example 4 and Step D of Example 83, the title compound was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09133129B2
Source datasetuspto-grants-2015_09
ORD IDord-523a86e6d94042bb8dc638331938765d
Source noteuspto-grants-2015_09