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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2277303Generated: November 1, 2026

2-[(1S)-2-Hydroxy-1-methylethyl]-1H-isoindole-1,3(2H)-dione → HCID 86731385, compound

https://huagongshe.com/reaction/2277303

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-[(1S)-2-Hydroxy-1-methylethyl]-1H-isoindole-1,3(2H)-dioneHCID 12499753—
Reactant5-Bromo-3-fluoro-1,2-dihydropyridin-2-oneHCID 178517594—
ProductHCID 86731385HCID 86731385—

Reaction Steps

Using 5-bromo-3-fluoropyridin-2-ol and 2-((2S)-1-hydroxypropan-2-yl)-1H-isoindole-1,3(2H)-dione, and in the same manner as in Step C of Example 1, the title compound was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09133129B2
Source datasetuspto-grants-2015_09
ORD IDord-29c4e9f52e2c421b97388d574e09618f
Source noteuspto-grants-2015_09