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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2277309Generated: October 30, 2026

tert-butyl ((2S)-1-((4-(benzyloxy)-5-nitropyrimidin-2-yl)oxy)propan-2-yl)carbamate → HCID 178461786, compound

https://huagongshe.com/reaction/2277309

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-butyl ((2S)-1-((4-(benzyloxy)-5-nitropyrimidin-2-yl)oxy)propan-2-yl)carbamateHCID 86731375—
Reactant5-(((1R)-2,2-difluorocyclopropyl)methoxy)-3-fluoropyridine-2-carboxylic AcidHCID 86731384—
ProductHCID 178461786HCID 178461786—

Reaction Steps

Using tert-butyl ((2S)-1-((4-(benzyloxy)-5-nitropyrimidin-2-yl)oxy)propan-2-yl)carbamate and 5-(((1R)-2,2-difluorocyclopropyl)methoxy)-3-fluoropyridine-2-carboxylic acid, and in the same manner as in Step A of Example 4 and Step D of Example 83, the title compound was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09133129B2
Source datasetuspto-grants-2015_09
ORD IDord-71ca2098d3bd44e78e920380efbedd95
Source noteuspto-grants-2015_09