Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2277328Generated: October 31, 2026

Bromomethylcyclopropane → N-((2S)-1-((2-(4-(cyclopropylmethoxy)-2-(difluoromethoxy)phenyl) [1,3]oxazolo[4,5-c]pyridin-6-yl)oxy)propan-2-yl)acetamide

https://huagongshe.com/reaction/2277328

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBromomethylcyclopropaneHCID 81503—
ReactantHCID 86731419HCID 86731419—
ProductN-((2S)-1-((2-(4-(cyclopropylmethoxy)-2-(difluoromethoxy)phenyl) [1,3]oxazolo[4,5-c]pyridin-6-yl)oxy)propan-2-yl)acetamideHCID 86731418—

Reaction Steps

Using N-((2S)-1-((2-(4-(benzyloxy)-2-(difluoromethoxy)phenyl) [1,3]oxazolo[4,5-c]pyridin-6-yl)oxy)propan-2-yl)acetamide and (bromomethyl)cyclopropane, and in the same manner as in Step D of Example 68, the title compound was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09133129B2
Source datasetuspto-grants-2015_09
ORD IDord-42aecfc56770407cb77ccc207df6cf3d
Source noteuspto-grants-2015_09