HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2,2-Difluoro-1-methylcyclopropyl)methanol → N-((2S)-1-((2-(4-((2,2-difluoro-1-methylcyclopropyl)methoxy)-3-fluorophenyl)[1,3]oxazolo[4,5-c]pyridin-6-yl)oxy)propan-2-yl)acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2,2-Difluoro-1-methylcyclopropyl)methanol | HCID 14695233 | — |
| Reactant | HCID 136341410 | HCID 136341410 | — |
| Product | N-((2S)-1-((2-(4-((2,2-difluoro-1-methylcyclopropyl)methoxy)-3-fluorophenyl)[1,3]oxazolo[4,5-c]pyridin-6-yl)oxy)propan-2-yl)acetamide | HCID 86731422 | — |
Reaction Steps
Using (2,2-difluoro-1-methylcyclopropyl)methanol and N-((2S)-1-((2-(3-fluoro-4-hydroxyphenyl)[1,3]oxazolo[4,5-c]pyridin-6-yl)oxy)propan-2-yl)acetamide, and in the same manner as in Step B of Example 4, the title compound was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09133129B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-d213687fbb534a8ba2fd31ff1b1e2098 |
| Source note | uspto-grants-2015_09 |