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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2277337Generated: October 29, 2026

4-(benzyloxy)-3,5-difluorobenzoic Acid → HCID 178461784, compound

https://huagongshe.com/reaction/2277337

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(benzyloxy)-3,5-difluorobenzoic AcidHCID 63183747—
Reactanttert-butyl ((2S)-1-((4-(benzyloxy)-5-nitropyrimidin-2-yl)oxy)propan-2-yl)carbamateHCID 86731375—
ProductHCID 178461784HCID 178461784—

Reaction Steps

Using tert-butyl ((2S)-1-((4-(benzyloxy)-5-nitropyrimidin-2-yl)oxy)propan-2-yl)carbamate and 4-(benzyloxy)-3,5-difluorobenzoic acid, and in the same manner as in Step A of Example 4, Step D of Example 83 and Step B of Example 123, the title compound was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09133129B2
Source datasetuspto-grants-2015_09
ORD IDord-409b50a9ff734434906b4b5cbfc7ec9c
Source noteuspto-grants-2015_09