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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2277444Generated: November 1, 2026

4-Cyclopropylbenzeneboronic acid → 2-[5-(4-cyclopropylphenyl)-1-methyl-1H-imidazol-4-yl]pyridine-4-carbonitrile

https://huagongshe.com/reaction/2277444

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Cyclopropylbenzeneboronic acidHCID 2849428—
Reactant2-(5-Bromo-1-methylimidazol-4-yl)pyridine-4-carbonitrileHCID 90408144—
Product2-[5-(4-cyclopropylphenyl)-1-methyl-1H-imidazol-4-yl]pyridine-4-carbonitrileHCID 90407845—

Reaction Steps

The title compound was prepared from 2-(5-bromo-1-methyl-1H-imidazol-4-yl)pyridine-4-carbonitrile and 4-cyclopropylphenylboronic acid according to the procedure for the preparation of Example 3, part A. [M+H] Calc'd for C19H16N4, 301. Found, 301.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09133166B2
Source datasetuspto-grants-2015_09
ORD IDord-f922e5fca84244f2bf16ff4eec97e6d4
Source noteuspto-grants-2015_09