[3-(Hydroxymethyl)phenyl]boronic acid → HCID 90407141, compound

HRID 2277448Notes

Reaction equation

HRID 2277448 reaction equation
Br[C:2]1[N:6]([CH3:7])[CH:5]=[N:4][C:3]=1[C:8]1[CH:13]=[C:12]([C:14]#[N:15])[CH:11]=[CH:10][N:9]=1.[OH:16][CH2:17][C:18]1[CH:19]=[C:20](B(O)O)[CH:21]=[CH:22][CH:23]=1>>[OH:16][CH2:17][C:18]1[CH:23]=[C:22]([C:2]2[N:6]([CH3:7])[CH:5]=[N:4][C:3]=2[C:8]2[CH:13]=[C:12]([C:14]#[N:15])[CH:11]=[CH:10][N:9]=2)[CH:21]=[CH:20][CH:19]=1

Participants

3

Reactant 2

HCID 2734662[3-(Hydroxymethyl)phenyl]boronic acidHCID 904081442-(5-Bromo-1-methylimidazol-4-yl)pyridine-4-carbonitrile

Product 1

HCID 90407141HCID 90407141, compound

Procedure

The title compound was prepared from 2-(5-bromo-1-methyl-1H-imidazol-4-yl)pyridine-4-carbonitrile and 3-hydroxymethylphenylboronic acid according to the procedure for the preparation of Example 3, part A. [M+H] Calc'd for C17H14N4O, 291. Found, 291.

Sources & evidence

ORD record
ord-e1a9d0340c4d4cd5b5c962fe79c5c240
Source dataset
uspto-grants-2015_09
Patent number
US09133166B2

Reaction notes

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