HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-4-cyanopyridine → 2-[1-(triphenylmethyl)-1H-imidazol-4-yl]pyridine-4-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-4-cyanopyridine | HCID 568638 | — |
| Reactant | 4-(Tributylstannyl)-1-tritylimidazole | HCID 11828117 | — |
| Product | 2-[1-(triphenylmethyl)-1H-imidazol-4-yl]pyridine-4-carbonitrile | HCID 90407660 | 77% |
Reaction Steps
The title compound was prepared in 77% yield from 2-chloro-4-pyridinenitrile and 4-(tributylstannyl)-1-tritylimidazole according to the procedure for Example 1, part A. 1H NMR (400 MHz, DMSO-d6): δ 7.17 (5H, m), 7.40-7.47 (10H, m), 7.49 (1H, d, J=1.2 Hz), 7.62 (1H, d, J=1.3 Hz), 7.65 (1H, dd, J=1.5 Hz and 5.0 Hz), 8.13 (1H, s), 8.67 (1H, d, 5.0 Hz).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09133166B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-a59fac35261b4e5c8949b3bb35a5d664 |
| Source note | uspto-grants-2015_09 |