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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2277488Generated: October 29, 2026

Pyridine, 2-(2-chloroethyl)-, hydrochloride → 2-[1-(pyridin-2-ylmethyl)-1H-imidazol-4-yl]pyridine-4-carbonitrile

https://huagongshe.com/reaction/2277488

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyridine, 2-(2-chloroethyl)-, hydrochlorideHCID 199467—
ReactantHCID 178510201HCID 178510201—
Product2-[1-(pyridin-2-ylmethyl)-1H-imidazol-4-yl]pyridine-4-carbonitrileHCID 90408112—

Reaction Steps

The title compound was prepared from 2-(1H-imidazol-4-yl)pyridine-4-carbonitrile and 2-(chloroethyl)pyridine hydrogen chloride according to the procedure for the preparation of Example 43, part A. [M+H] Calc'd for C15H11N5, 262. Found, 262.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09133166B2
Source datasetuspto-grants-2015_09
ORD IDord-9154048d3df644e99bd85bcb101900b1
Source noteuspto-grants-2015_09