HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Benzyloxy-4-fluorophenylboronic acid → 2-[5-(4-Fluoro-2-phenylmethoxyphenyl)-1-methylimidazol-4-yl]pyridine-4-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Benzyloxy-4-fluorophenylboronic acid | HCID 2782665 | — |
| Reactant | 2-(5-Bromo-1-methylimidazol-4-yl)pyridine-4-carbonitrile | HCID 90408144 | — |
| Product | 2-[5-(4-Fluoro-2-phenylmethoxyphenyl)-1-methylimidazol-4-yl]pyridine-4-carbonitrile | HCID 90408142 | — |
Reaction Steps
The title compound was prepared from 2-(5-bromo-1-methyl-1H-imidazol-4-yl)pyridine-4-carbonitrile (PREPARATION 2) and 2-benzyloxyl-4-fluorophenylboronic acid according to the procedure for the preparation of Example 3, part A. [M+H] Calc'd for C23H17FN4O, 385. Found, 385.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09133166B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-44a9609decb34573b453b8fbda47ffe3 |
| Source note | uspto-grants-2015_09 |