HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 86685963, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 86685964 | HCID 86685964 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 86685963 | HCID 86685963 | — |
Reaction Steps
In analogy to the procedure described in example 135 [D], 2-{5-[(R)-3-(tert-butyl-dimethyl-silanyloxy)-pyrrolidin-1-yl]-pyridin-3-yl}-6-chloro-3,4-dihydro-2H-isoquinolin-1-one was deprotected with 4M HCl in dioxane to give the title compound as a white foam. MS: 344.0 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09133158B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-a3af7dc5c4334e0ba27c4a09c7320142 |
| Source note | uspto-grants-2015_09 |