HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-5-fluoro-4-(4-fluoro-2-methoxyphenyl)pyrimidine → HCID 89444641, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-5-fluoro-4-(4-fluoro-2-methoxyphenyl)pyrimidine | HCID 86729609 | — |
| Reactant | HCID 89262622 | HCID 89262622 | — |
| Product | HCID 89444641 | HCID 89444641 | — |
Reaction Steps
Intermediate 58.3 was prepared under similar conditions as described in the preparation of Intermediate 20.1 using 2-chloro-5-fluoro-4-(4-fluoro-2-methoxyphenyl)pyrimidine and 3-methyl-5-[(methyl-sulfanyl)methyl]aniline. The batch was purified by chromatography (hexane/ethyl acetate 5% to 32%) to give the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09133171B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-23bbb9b3db7c43308c3e1b85360cae55 |
| Source note | uspto-grants-2015_09 |