Pyrrolidine → HCID 89682822, compound

HRID 2278238Notes

Reaction equation

HRID 2278238 reaction equation
F[C:2]1[CH:9]=[C:8]([C:10]([F:13])([F:12])[F:11])[CH:7]=[CH:6][C:3]=1[CH:4]=[O:5].[NH:14]1[CH2:18][CH2:17][CH2:16][CH2:15]1>>[N:14]1([C:2]2[CH:9]=[C:8]([C:10]([F:13])([F:12])[F:11])[CH:7]=[CH:6][C:3]=2[CH:4]=[O:5])[CH2:18][CH2:17][CH2:16][CH2:15]1

Participants

3

Reactant 2

HCID 31268PyrrolidineHCID 5229292-Fluoro-4-(trifluoromethyl)benzaldehyde

Product 1

HCID 89682822HCID 89682822, compound

Procedure

The title compound was synthesized from 2-fluoro-4-(trifluoromethyl)benzaldehyde and pyrrolidine as described in Example 67, Step 1 (1.6 g, 63%): LCMS (ESI, m/z): 244 [M+H]+.

Sources & evidence

ORD record
ord-3509b14ec7694bfe8beb09f40ee9528d
Source dataset
uspto-grants-2015_09
Patent number
US09133148B2

Reaction notes

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