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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2278239Generated: October 30, 2026

Pyrrolidine → HCID 89677025, compound

https://huagongshe.com/reaction/2278239

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyrrolidineHCID 31268—
Reactant3-Chloro-2-fluorobenzaldehydeHCID 736335—
ProductHCID 89677025HCID 89677025—

Reaction Steps

The title compound was synthesized from 3-chloro-2-fluorobenzaldehyde and pyrrolidine as described in Example 67, Step 1 (800 mg, 30%). 1H NMR 300 MHz (CDCl3) δ 10.36 (s, 1H), 7.71-7.73 (m, 1H), 7.59-7.61 (m, 1H), 7.18-7.26 (m, 1H), 3.33-3.42 (m, 4H), 2.01-2.10 (m, 4H). LCMS (ESI, m/z): 210 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09133148B2
Source datasetuspto-grants-2015_09
ORD IDord-bad290b96ebf42cabc90acfd00607935
Source noteuspto-grants-2015_09