反应详情

温度

80 °C

A solution of hippuric acid (4.0 g, 1.0 eq.) was added to a solution acetic anhydride (10 mL), 1-naphthylaldehyde (3.84 g, 1.1 eq.) and sodium acetate (2.21 g, 1.2 eq.). The reaction mixture was then heated at 80° C. for 2 hours, then cooled to room temperature, filtered, and washed with acetic anhydride. After air drying, the solid was washed back with water and air-dried overnight to give the desired compound.

1. temperaturecooled to room temperature
2. filtrationfiltered
3. washwashed with acetic anhydride
4. customAfter air drying
5. washthe solid was washed back with water
6. customair-dried overnight