3-Chloro-4-fluoroaniline → HCID 57406394, compound

Participants

Reaction Steps

The product is prepared by following the procedure described in step 3b of example 1b, but using 250 mg of the sodium salt of [4-(2-fluoromethylmorpholin-4-yl)-1-methyl-6-oxo-1,6-dihydropyrimidin-2-yl]acetic acid and 237 mg of 3-chloro-4-fluoroaniline. 97 mg of 2-[4-(2-fluoromethylmorpholin-4-yl)-1-methyl-6-oxo-1,6-dihydropyrimidin-2-yl]-N-(3-chloro-4-fluorophenyl)acetamide are obtained in the form of a white solid, the characteristics of which are the following:

Provenance & Evidence