1'-Methylspiro[indoline-3,4'-piperidine] → HCID 136128233, compound

Participants

Reaction Steps

The product is prepared by following the procedure described in example 10d using 35.5 mg of sodium [4-(morpholin-4-yl)-6-oxo-1,6-dihydropyrimidin-2-yl]acetate (example 1d, step 2d) and 25 mg of 1′-methylspiro[indoline-3,4′-piperidine] in place of 4-pyridin-4-yl-2,3-dihydro-1H-indole. 13.8 mg of 212-r-methylspiro[indole-3,4′-piperidin]-1(2H)-yl)-2-oxoethyl]-6-(morpholin-4-yl)pyrimidin-4(3H)-one are obtained in the form of a pale pink powder, the characteristics of which are the following:

Provenance & Evidence