Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | HCID 71745308 | HCID 71745308 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 66671444 | HCID 66671444 | — |
Reaction Steps
To a solution of 4-(6-chloro-9-methyl-9H-purin-2-yl)but-3-yn-1-ol (650 mg, 2.74 mmol) in dioxane (4 ml) was added 30% w/w water solution of ammonia (8 ml). The reaction mixture was stirred overnight in an autoclave at 70° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US09133197B2 |
|---|
| Source dataset | uspto-grants-2015_09 |
|---|
| ORD ID | ord-0d2ea8928b234b9faeec47b26fca7ca3 |
|---|
| Source note | uspto-grants-2015_09 |
|---|
