HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 46912313, compound → HCID 46912316, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 46912313 | HCID 46912313 | — |
| Catalyst | Manganese dioxide | HCID 14801 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 46912316 | HCID 46912316 | 40% |
Reaction Steps
MnO2 (439 mg, 5.04 mmol) was added to a solution of 1-(6-amino-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-2-yl)butan-1-ol (51 mg, 0.2 mmol) in DCM (4 ml) at RT. The resulting heterogeneous solution was stirred overnight. After filtration over a celite pad, the solvent was removed under reduced pressure to afford the desired product as a white powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09133197B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-58e9b14bd777454bb02dc512d26441ff |
| Source note | uspto-grants-2015_09 |