HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Methoxypropylamine → HCID 90427351, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Methoxypropylamine | HCID 1672 | — |
| Reactant | 2-Chloroethyl isocyanate | HCID 16035 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 90427351 | HCID 90427351 | 100% |
Reaction Steps
A solution of 3-methoxypropylamine (0.45 mL, 4.39 mmol) in THF (15 mL) was treated with 2-chloroethylisocyanate (0.35 mL, 4.10 mmol), stirred at RT for 3 h and concentrated to dryness to afford 1-(2-chloroethyl)-3-(3-methoxypropyl)urea (100% yield assumed) as a white solid. MS (ESI) m/z: 195.1 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09133183B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-ab085320ef1749a8a1a2798955f76256 |
| Source note | uspto-grants-2015_09 |