HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 178434387, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 4-[3-Methyl-1-(tetrahydro-pyran-2-yl)-4-(2,2,5,5-tetramethyl-piperazin-1-ylmethyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]-phenol | HCID 136623191 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 178434387 | HCID 178434387 | — |
Reaction Steps
150 mg 4-[3-methyl-1-(tetrahydro-pyran-2-yl)-4-(2,2,5,5-tetramethyl-piperazin-1-ylmethyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]-phenol were dissolved in 10 ml of tetrahydrofurane and 0.65 ml HCl (4N in 1,4-dioxane) were added. After stirring the reaction at r.t. for 30 min the precipitated residue was isolated by filtration and washed with THF.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09133181B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-c3c0a1e0f5044e3eae258b19f07c7d30 |
| Source note | uspto-grants-2015_09 |