反应详情

65 mg of 6-(4-Methoxymethoxy-phenyl)-3-methyl-1-(tetrahydro-pyran-2-yl)-4-(2,2,5-trimethyl-4-pyridin-3-ylmethyl-piperazin-1-ylmethyl)-1H-pyrazolo[3,4-b]pyridine were dissolved in 1.5 ml of 1,4-dioxane and treated with 1.5 ml of hydrochloric acid (4 M in dry dioxane). After standing at rt for 10 min the volatiles were removed in vacuo. The residue purified by HPLC and 65 mg of the title compound were obtained.

1. customthe volatiles were removed in vacuo
2. customThe residue purified by HPLC