Hydrochloric Acid → HCID 178465270, compound

Participants

Reaction Steps

325 mg of 4-[6-(4-Methoxymethoxy-phenyl)-3-methyl-1-(tetrahydro-pyran-2-yl)-1H-pyrazolo[3,4-b]pyridin-4-ylmethyl]-2,2,5,5-tetramethyl-piperazine-1-carboxylic acid ethylamide in 2 ml of dioxane were reacted with 2 ml hydrochloric acid (4M in dioxane). After 4 h at rt the volatiles were removed in vacuo. After purification by preparative HPLC 142 mg (56%) of the title compound were obtained.

Provenance & Evidence