Hydrochloric Acid → HCID 178496353, compound

Participants

Reaction Steps

93 mg of 2-Methoxy-1-{4-[6-(4-methoxymethoxy-phenyl)-3-methyl-1-(tetrahydro-pyran-2-yl)-1H-pyrazolo[3,4-b]pyridin-4-ylmethyl]-2,2,5,5-tetramethyl-piperazin-1-yl}-ethanone were dissolved in 2.5 ml of dioxane and reacted with 2 ml hydrochloric acid (4M in dioxane). The volatiles were removed after 16 h. After purification by preparative HPLC 25 mg of the title compound were obtained.

Provenance & Evidence