2-Tetrahydropyranyl 4-benzyloxycarbonylaminobicyclo[2,2,2]octane-1-carboxylate → 2-Tetrahydropyranyl 4-aminobicyclo[2,2,2]octane-1-carboxylate

참여 물질

반응 단계

2-Tetrahydropyranyl 4-benzyloxycarbonylaminobicyclo[2.2.2]octane-1-carboxylate (548 mg) was dissolved in ethanol (6 mL). To this solution, 10% palladium-carbon (60 mg) was added and the mixture was stirred at room temperature for 2 hours in a stream of hydrogen. The catalyst in the reaction mixture was filtered through a Celite pad and the filtered catalyst, together with the Celite pad, washed with ethanol. The filtrate and the washings were combined and concentrated under reduced pressure. The resulting residue was dried under reduced pressure to give 2-tetrahydropyranyl 4-aminobicyclo[2.2.2]octane-1-carboxylate (357 mg).

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