HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 86705574, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 68294972 | HCID 68294972 | — |
| Product | HCID 86705574 | HCID 86705574 | — |
Reaction Steps
A solution of 326 (56 mg, 0.18 mmol) and TFA (2 mL) and was stirred at RT for 45 min. The reaction was concentrated to provide crude (S)-2-(5,6,7,8-tetrahydro-2,6-naphthyridin-3-ylamino)propan-1-ol 2,2,2-trifluoroacetate (328) which was used in the nest step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09133187B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-ff63dda537324b709284f233fa31dd32 |
| Source note | uspto-grants-2015_09 |