HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2279642Generated: October 30, 2026
Sodium Hydroxide → 5-Benzyl-1,3-dimethyl-1H-pyrazole-4-carboxylic acid
https://huagongshe.com/reaction/2279642
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 5-benzyl-1,3-dimethyl-1H-pyrazole-4-carboxylic acid methyl ester | HCID 15446227 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 5-Benzyl-1,3-dimethyl-1H-pyrazole-4-carboxylic acid | HCID 59579984 | — |
Reaction Steps
NaOH (10 N, 7 mL) is added to a solution of 5-benzyl-1,3-dimethyl-1H-pyrazole-4-carboxylic acid methyl ester (680 mg, 2.78 mmol) in MeOH (10 mL) at RT. The mixture is heated to 50° C. for 4 h. The solvent is removed to dryness. H2O is added and pH is adjusted to 5 using aq. HCl. The solid is filtered and dried to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US09133204B2 |
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| Source dataset | uspto-grants-2015_09 |
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| ORD ID | ord-addbbf4343454f61b3a7044fb462cd9f |
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| Source note | uspto-grants-2015_09 |
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