反应详情

1-({3-[(Benzyloxy)methyl]oxetan-3-yl}methyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (Compound 44C, 1.37 mg, 3.56 mmol) was hydrogenated using the procedure from Compound 38A to afford 998 mg of the title compound (95%). 1H NMR (400 MHz, CD3OD) δ 7.86 (s, 1H), 7.67 (s, 1H), 4.65 (d, J=6.3 Hz, 2H), 4.49 (s, 2H), 4.42 (d, J=6.3 Hz, 2H), 3.57 (s, 2H), 1.32 (s, 12H).