Hydrochloric Acid → HCID 86707566, compound

HRID 2279964Notes

Reaction equation

HRID 2279964 reaction equation
COCCOC[O:7][C:8]1[CH:9]=[C:10]([C:31]2[CH:36]=[CH:35][C:34]([O:37][CH2:38][CH2:39][CH2:40][O:41]C3CCCCO3)=[CH:33][CH:32]=2)[CH:11]=[C:12]([C:14]2[CH:19]=[CH:18][C:17]([O:20][CH2:21][CH2:22][CH2:23][O:24]C3CCCCO3)=[CH:16][CH:15]=2)[CH:13]=1.Cl>CO.O>[OH:41][CH2:40][CH2:39][CH2:38][O:37][C:34]1[CH:33]=[CH:32][C:31]([C:10]2[CH:9]=[C:8]([OH:7])[CH:13]=[C:12]([C:14]3[CH:19]=[CH:18][C:17]([O:20][CH2:21][CH2:22][CH2:23][OH:24])=[CH:16][CH:15]=3)[CH:11]=2)=[CH:36][CH:35]=1

Participants

5

Reactant 2

HCID 313Hydrochloric AcidHCID 86707567HCID 86707567, compound

Product 1

HCID 86707566HCID 86707566, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 962WaterSolvent

Procedure

7.90 g (12.1 mmol) 3′-[5′-(2-methoxy-ethoxymethoxy)-[1,1′:3′,1″-terphenyl]-4,4″-diylbis(oxy-3,1-propanediyloxy)]bis(tetrahydro-2H-pyrane) are dissolved in 60 ml methanol, and, after addition of 9 ml conc. hydrochloric acid, stirred overnight at RT. The mixture is diluted with water and extracted three times with MTB ether. The combined organic layers are washed with sat. aq. sodium chloride solution and dried over sodium sulfate. 4,4″-Bis-(3-hydroxy-propoxy)-[1,1′;3′,1″]terphenyl-5′-ol is obtained as a yellow oil.

Workup

  1. extractionextracted three times with MTB ether
  2. washThe combined organic layers are washed with sat. aq. sodium chloride solution
  3. dry with materialdried over sodium sulfate

Sources & evidence

ORD record
ord-c9bdc42494754f3caf93bbb7fcb2adb0
Source dataset
uspto-grants-2015_09
Patent number
US09133395B2

Reaction notes

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