HCID 86702659, compound → HCID 86702658, compound

HRID 2280051Notes

Reaction equation

HRID 2280051 reaction equation
[C:1]1(/[CH:7]=[CH:8]/[CH2:9][CH2:10][CH2:11][C:12]#[C:13][C:14](=[O:16])[CH3:15])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1>ClCCCl>[CH2:9]1[C:8]2=[CH:7][C:1]3[C:6]([C:13]([C:14](=[O:16])[CH3:15])=[C:12]2[CH2:11][CH2:10]1)=[CH:5][CH:4]=[CH:3][CH:2]=3

Participants

3

Reactant 1

HCID 86702659HCID 86702659, compound

Product 1

HCID 86702658HCID 86702658, compound

Reagents, catalysts & solvents 1

HCID 111,2-DichloroethaneSolvent

Conditions

Temperature
180 °C

Procedure

To a 0.5-2 mL microwave irradiation vial equipped with a stir bar was added enyne 5a (0.020 g, 0.094 mmol) in DCE (1.6 mL). The reaction was irradiated with stirring at 180° C. for 30 min until complete by TLC. The reaction turned golden in color. The reaction was then transferred to a vial, concentrated under reduced pressure, and dried under vacuum to yield naphthalene 6a as a black oil (0.020 g, quant.).

Workup

  1. customTo a 0.5-2 mL microwave irradiation
  2. customvial equipped with a stir bar
  3. customThe reaction was irradiated
  4. concentrationconcentrated under reduced pressure
  5. customdried under vacuum

Sources & evidence

ORD record
ord-15ba7f22b0104297afa6bd7ae1bc2360
Source dataset
uspto-grants-2015_09
Patent number
US09133234B2

Reaction notes

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