HCID 66575152, compound → HCID 66575153, compound

HRID 2280052Notes

Reaction equation

HRID 2280052 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5](/[CH:8]=[CH:9]/[CH2:10][CH2:11][CH2:12][C:13]#[C:14][C:15](=[O:17])[CH3:16])=[CH:4][CH:3]=1>ClCCCl>[Cl:1][C:2]1[CH:3]=[C:4]2[C:5](=[CH:6][CH:7]=1)[CH:8]=[C:9]1[CH2:10][CH2:11][CH2:12][C:13]1=[C:14]2[C:15](=[O:17])[CH3:16]

Participants

3

Reactant 1

HCID 66575152HCID 66575152, compound

Product 1

HCID 66575153HCID 66575153, compound

Reagents, catalysts & solvents 1

HCID 111,2-DichloroethaneSolvent

Conditions

Temperature
180 °C

Procedure

To a 2-5 mL microwave irradiation vial equipped with a stir bar was added enyne 5b (0.028 g, 0.12 mmol) in DCE (2.1 mL). The reaction was irradiated with stirring at 180° C. for 200 min until complete by TLC. The reaction turned golden in color. The reaction was then transferred to a vial, concentrated under reduced pressure, and dried under vacuum to yield naphthalene 6b as a brown oil (0.027 g, quant.).

Workup

  1. customTo a 2-5 mL microwave irradiation
  2. customvial equipped with a stir bar
  3. customThe reaction was irradiated
  4. concentrationconcentrated under reduced pressure
  5. customdried under vacuum

Sources & evidence

ORD record
ord-e034742b9b4f4713902232a2d57fd98a
Source dataset
uspto-grants-2015_09
Patent number
US09133234B2

Reaction notes

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