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HRID228008

反应详情

EQUATION

反应方程式

HRID 228008 的结构方程式

REACTANTS

反应物

2
结构：Nc1ccc(Cc2ccccc2)cc1
HCID136914

Benzenamine, 4-(phenylmethyl)-

C13H13N

结构：N#C[C@@H]1C[C@H](F)CN1C(=O)CNC12CCC(C(=O)O)(CC1)CC2
HCID57634365

未命名化合物

PRODUCTS

生成物

1
结构：N#C[C@@H]1C[C@H](F)CN1C(=O)CNC12CCC(C(=O)Nc3ccc(Cc4ccccc4)cc3)(CC1)CC2
HCID57756732

未命名化合物

收率 41.2%

PROCEDURE

实验过程

In a similar manner to Example 63, (2S,4S)-1-[[N-(4-carboxybicyclo[2.2.2]oct-1-yl)amino]acetyl]-4-fluoropyrrolidine-2-carbonitrile (50.0 mg) and 4-aminodiphenylmethane (62.0 mg) were used to obtain (2S,4S)-4-fluoro-1-[[N-[4-[N-(4-phenylmethylphenyl)amino]carbonylbicyclo[2.2.2]oct-1-yl]amino]acetyl]pyrrolidine-2-carbonitrile (31.1 mg).