HCID 71208067, compound → HCID 71208634, compound

Participants

Reaction Conditions

Reaction Steps

tert-butyl 6-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)-1,4-oxazepane-4-carboxylate is dissolved in acetone and 6N aqueous hydrochloric acid. The reaction is then heated at 45° C. which yielded a precipitate. After 2.5 hours, the precipitate is collected by vacuum filtration, washed with a minimal amount of acetone and dried on the lyophilizer to afford title compound.

Provenance & Evidence