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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 228045Generated: October 26, 2026

Benzenamine, 4-chloro-2-(trifluoromethyl)- → HCID 23150549, compound

https://huagongshe.com/reaction/228045

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzenamine, 4-chloro-2-(trifluoromethyl)-HCID 67961—
Reactant4-{[(Tert-butoxy)carbonyl]amino}bicyclo[2.2.2]octane-1-carboxylic acidHCID 23150738—
ProductHCID 23150549HCID 23150549—

Reaction Steps

In a similar manner to Example 133, 4-tert-butoxycarbonylaminobicyclo[2.2.2]octane-1-carboxylic acid (150 mg) and 2-amino-5-chlorobenzotrifluoride (173 μL) were used to obtain 4-tert-butoxycarbonylamino-N-(4-chloro-2-trifluoromethylphenyl)bicyclo[2.2.2]octane-1-carboxamide (79.7 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07560569B2
Source datasetuspto-grants-2009_07
ORD IDord-783b1943a1ab4a6891dd2fd1f5e19d51
Source noteuspto-grants-2009_07