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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 228048Generated: October 25, 2026

2-Fluoro-4-(trifluoromethyl)aniline → HCID 23150664, compound

https://huagongshe.com/reaction/228048

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Fluoro-4-(trifluoromethyl)anilineHCID 2737674—
Reactant4-{[(Tert-butoxy)carbonyl]amino}bicyclo[2.2.2]octane-1-carboxylic acidHCID 23150738—
ProductHCID 23150664HCID 23150664—

Reaction Steps

In a similar manner to Example 133, 4-tert-butoxycarbonylaminobicyclo[2.2.2]octane-1-carboxylic acid (100 mg) and 4-amino-3-fluorobenzotrifluoride (106 μL) were used to obtain 4-tert-butoxycarbonylamino-N-(2-fluoro-4-trifluoromethylphenyl)bicyclo[2.2.2]octane-1-carboxamide (58.6 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07560569B2
Source datasetuspto-grants-2009_07
ORD IDord-3e0ed2d8e2ac4dbba4906dbc572c3207
Source noteuspto-grants-2009_07