HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 2-[4-benzylpiperazinyl]benzoate → Methyl 2-(piperazin-1-yl)benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 2-[4-benzylpiperazinyl]benzoate | HCID 21935101 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | Methyl 2-(piperazin-1-yl)benzoate | HCID 10932975 | — |
Reaction Steps
The title compound was prepared according to the procedure described in Preparation IV by using methyl 2-[4-benzylpiperazinyl]benzoate (2.8 g, 8.9 mmol), 10% Pd/C (Aldrich) (940 mg), and HCO2NH4 (2.8, 44 mmol). The title compound was isolated as a colorless oil (1.75 g). (MS (ESI, pos. ion) m/z: 221 (M+H). Calc'd for C12H16N2O2: 220.12.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07560460B2 |
| Source dataset | uspto-grants-2009_07 |
| ORD ID | ord-01e8de75eefe4ceb950ef10f879436f3 |
| Source note | uspto-grants-2009_07 |