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HRID2281343

反应详情

EQUATION

反应方程式

HRID 2281343 的结构方程式

REACTANTS

反应物

2
结构：O=S(=O)(Cl)c1ccc(-n2cnnn2)cc1
HCID43363641

未命名化合物

结构：Cc1c([C@@H](O)CN2C[C@H]3CC[C@@H](C2)N3)ccc2c1COC2=O.Cl
HCID117642133

未命名化合物

2 次

PRODUCTS

生成物

1
结构：Cc1c([C@@H](O)CN2C[C@@H]3C[C@H]2CN3S(=O)(=O)c2ccc(-n3cnnn3)cc2)ccc2c1COC2=O
HCID71557031

未命名化合物

PROCEDURE

实验过程

5-((R)-1-Hydroxy-2-((1S,4S)-5-(4-(1H-tetrazol-1-yl)phenylsulfonyl)-2,5-diazabicyclo[2.2.1]heptan-2-yl)ethyl)-4-methylisobenzofuran-1 (3H)-one was prepared in a similar fashion to that described for the synthesis of EXAMPLE 14 starting from 5-((R)-2-((1R,5S)-3,8-diazabicyclo[3.2.1]octan-3-yl)-1-hydroxyethyl)-4-methylisobenzofuran-1(3H)-one hydrochloride (INTERMEDIATE 15) and commercially available 4-(1H-tetrazol-1-yl)benzene-1-sulfonyl chloride.