Phenethylamine → HCID 59730395, compound

HRID 228182Notes

Reaction equation

[CH2:1]([O:3][C:4]1[CH:19]=[C:18]([CH:20]=O)[CH:17]=[CH:16][C:5]=1[O:6][C:7]1[CH:15]=[CH:14][C:10]([C:11]([NH2:13])=[O:12])=[CH:9][N:8]=1)[CH3:2].[CH2:22]([NH2:30])[CH2:23][C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1>>[CH2:1]([O:3][C:4]1[CH:19]=[C:18]([CH2:20][NH:30][CH2:22][CH2:23][C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)[CH:17]=[CH:16][C:5]=1[O:6][C:7]1[CH:15]=[CH:14][C:10]([C:11]([NH2:13])=[O:12])=[CH:9][N:8]=1)[CH3:2]

Participants

Reactant 2

HCID 1001Phenethylamine

HCID 59730044HCID 59730044, compound

Product 1

HCID 59730395HCID 59730395, compoundYield 99%

Procedure

The compound of example 224 step 1 was reductively aminated with phenethylamine using procedures similar to those previously described to afford the title compound in 99% yield.

Sources & evidence

ORD record: ord-01918aa0da79434ca2e3ceb14103d3de
Source dataset: uspto-grants-2009_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07560463B2

Reaction notes

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