Piperidine → Methyl(2-(piperidin-1-yl)ethyl)amine

HRID 2281947Notes

Reaction equation

HRID 2281947 reaction equation
[NH:1]1[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.N[CH2:8][C@@H:9]1CC[CH2:11][N:10]1CC>>[CH3:11][NH:10][CH2:9][CH2:8][N:1]1[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 8082PiperidineHCID 643457(S)-(-)-2-Aminomethyl-1-ethylpyrrolidine

Product 1

HCID 3157473Methyl(2-(piperidin-1-yl)ethyl)amine

Procedure

By using piperidine (983.5 mg) as a starting material, the title compound (120 mg) was obtained in the same manners as those of Reference Example 1, (1) and Reference Example 19, (3).

Sources & evidence

ORD record
ord-cc2fd28663af46f8a7652299d95e157d
Source dataset
uspto-grants-2015_09
Patent number
US09139609B2

Reaction notes

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