Acetaldehyde → N-Methyl-3-(morpholin-4-yl)propan-1-amine

HRID 2281961Notes

Reaction equation

[NH2:1][CH2:2][CH2:3][CH2:4][N:5]1[CH2:10][CH2:9][O:8][CH2:7][CH2:6]1.[CH:11](=O)C>>[CH3:11][NH:1][CH2:2][CH2:3][CH2:4][N:5]1[CH2:10][CH2:9][O:8][CH2:7][CH2:6]1

Participants

Reactant 2

HCID 177Acetaldehyde2×

HCID 61055N-(3-Aminopropyl)morpholine

Product 1

HCID 22594078N-Methyl-3-(morpholin-4-yl)propan-1-amine

Procedure

By using N-(3-aminopropyl)morpholine (1.0 g) as a starting material, the title compound (57 mg) was obtained in the same manners as those of Reference Example 51, (1), Reference Example 8, (2) and Reference Example 19, (3).

Sources & evidence

ORD record: ord-49379702e5da47bb90ab578b00980db1
Source dataset: uspto-grants-2015_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09139609B2

Reaction notes

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