Acetaldehyde → HCID 19914557, compound

HRID 2281972Notes

Reaction equation

C(OC([NH:8][CH2:9][C:10](O)=[O:11])=O)(C)(C)C.[N:13]1[CH:18]=[CH:17][CH:16]=[C:15]([CH2:19][NH2:20])[CH:14]=1.NC[C@@H]1CCCN1CC.C(=O)C>>[NH2:8][CH2:9][C:10]([NH:20][CH2:19][C:15]1[CH:14]=[N:13][CH:18]=[CH:17][CH:16]=1)=[O:11]

Participants

Reactant 4

HCID 177Acetaldehyde

HCID 310183-Pyridinemethanamine

HCID 78288N-(tert-butoxycarbonyl)glycine

HCID 643457(S)-(-)-2-Aminomethyl-1-ethylpyrrolidine

Product 1

HCID 19914557HCID 19914557, compound

Procedure

By using N-(t-butoxycarbonyl)glycine (1.0 g) and 3-picolylamine (577 μl) as starting materials, the title compound (892 mg) was obtained in the same manners as those of Reference Example 88, (1) and Reference Example 78, (3).

Sources & evidence

ORD record: ord-5a481ad3c82c46ddbf3c861804d7bc8d
Source dataset: uspto-grants-2015_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09139609B2

Reaction notes

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