HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxycodone Hydrochloride → Oxycodone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxycodone Hydrochloride | HCID 5462350 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | Oxycodone | HCID 5284603 | 93% |
Reaction Steps
Oxycodone hydrochloride (10.0 g, 28.5 mmol) was dissolved in chloroform (150 mL) and washed with 5% aq. NaHCO3 (50 mL). The organic layer was dried over MgSO4 and evaporated. The residue was dried under vacuum overnight to provide oxycodone free base (8.3 g, 93%) as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09139612B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-45d7bf76e1df4894bd5f1cd7b4e8496a |
| Source note | uspto-grants-2015_09 |